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Filtering by: Creator Dent, William Elmer Remove constraint Creator: Dent, William Elmer Advisor Gerwick, William H. Remove constraint Advisor: Gerwick, William H.

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  • The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

    Creator:
    Lopez, Albert
    Abstract:
    The sea offers a wide variety of potentially useful resources. Marine algae have been a rich source of structurally unique natural products showing diverse biological properties. The current need to develop new antifungal, antibiotic, anticancer and antiviral drugs has prompted intense research efforts into the discovery, isolation and structure determination...
    Resource Type:
    Masters Thesis
    Full Text:
    Ptilota filicina and Laurencia obtusa Abstract approved: Redacted for Privacy Dr. William H. Gerwick

  • Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

    Creator:
    Han, Bingnan
    Abstract:
    This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
    Resource Type:
    Dissertation
    Full Text:
    gratitude to my major advisor, Dr. William Gerwick, and my committee members, Dr. Philip Proteau, Dr

  • Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

    Creator:
    Nogle, Lisa Marie
    Abstract:
    This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
    Resource Type:
    Dissertation
    Full Text:
    Biosynthetic Investigations of Marine Cyanobacterial Secondary Metabolites Abstract approved William H

  • Natural products from tropical and temperate marine algae

    Creator:
    Bernart, Matthew W.
    Abstract:
    Following surveys of seaweeds in Oregon and the Caribbean, four algal species were selected for study on the basis of their crude extract biological activity or thin-layer chromatographic characteristics. Extracts were fractionated by normal phase chromatography, including high performance liquid chromatography (HPLC). Derivatives (methyl esters, acetates, and benzoates) of natural...
    Resource Type:
    Dissertation
    Full Text:
    Algae Abstract approved: Redacted for Privacy William H. Gerwick Following surveys of seaweeds in

  • Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

    Creator:
    Milligan, Kenneth Edward
    Abstract:
    This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...
    Resource Type:
    Dissertation
    Full Text:
    Secondary Metabolites of Unique Structure and Biomedicinal or Agrichemical Potential. Abstract William H

  • New bioactive natural products from marine algae and cyanobacteria

    Creator:
    Sabry, Omar Mohamed
    Abstract:
    This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
    Resource Type:
    Dissertation
    Full Text:
    I would like to thank my major advisor, Dr. William H. Gerwick, for his exceptional generous

  • Natural products studies of the marine cyanobacterium Lyngbya majuscula

    Creator:
    Sitachitta, Namthip
    Abstract:
    The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
    Resource Type:
    Dissertation
    Full Text:
    ------------ William H. Gerwick The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich

  • Oxylipins from temperate marine algae and a photoprotective sheath pigment from blue-green algae

    Creator:
    Proteau, Philip J.
    Resource Type:
    Dissertation
    Full Text:
    Marine Algae and a Photoprotective Sheath Pigment from Blue-Green Algae Abstract approved: William

  • Novel secondary metabolites from a Madagascar collection of Lyngbya majuscula

    Creator:
    Nannini, Christopher J.
    Abstract:
    Marine organisms produce a variety of secondary metabolites for defense, communication, and reproduction. While these uses are essential for the organisms' survival, marine natural products have demonstrated their value to human society as well. Asian countries used algae for centuries to treat or prevent illnesses as wide-ranging as cough, gout,...
    Resource Type:
    Masters Thesis
    Full Text:
    from a Madagascar Collection of Lyngbya ma/uscula. Abstract approved William H. Gerwick Marine

  • Bioactive natural products from marine algae

    Creator:
    Tan, Lik Tong
    Abstract:
    This thesis is an account of my investigation on the natural products deriving from various marine algae and has resulted in the discovery of thirteen novel bioactive metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D...
    Resource Type:
    Dissertation
    Full Text:
    2001. Title: Bioactive Natural Products from Marine Algae. Abstract approved: William H. Gerwick This