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Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Creator:: Marquez, Brian L.
Abstract:: This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE THESIS OF Brian L. Marguez for the degree of

Oxylipins from temperate marine algae and a photoprotective sheath pigment from blue-green algae

Creator:: Proteau, Philip J.
Resource Type:: Dissertation
Full Text:: sheath pigment from blue-green algae AN ABSTRACT OF THE THESIS OF Philip J. Proteau for the degree

Natural products from temperate and tropical marine algae

Creator:: Graber, Melodie A.
Resource Type:: Masters Thesis
Full Text:: . Constantine, Philip J. Proteau and Douglas Markle for their advice and assistance. I especially thank Dr

Novel bioactive secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Creator:: Wu, Min, 1963-
Abstract:: Marine algae have been recognized as a rich resource of new and unusual organic molecules with diverse biological properties. The current need to develop new antifungal, anticancer, antibiotic and antiviral drugs has led to an intense research effort into the discovery, isolation and structure determination of potential medicinal agents from...
Resource Type:: Masters Thesis
Full Text:: , malyngamide J and malyngamide L. The structures of these new compounds, including stereochemistry, were

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: throughout my graduate career at Oregon State University. I would also like to acknowledge Brian Arbogast

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Creator:: Milligan, Kenneth Edward
Abstract:: This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...
Resource Type:: Dissertation
Full Text:: Chemistry NMR), Brian Arborgast (Dept. of Chemistry EIHMS), and the laboratory of Dr. Victor Hsu (600 MHz

New bioactive natural products from marine algae and cyanobacteria

Creator:: Sabry, Omar Mohamed
Abstract:: This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Resource Type:: Dissertation
Full Text:: to Jeff More and Brian Arbogast (Department of Chemistry, OSU) for their extensive mass spectral

Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

Creator:: Yoo, Hye-Dong
Abstract:: My investigations of the natural products of marine algae have resulted in the discovery of several new secondary metabolites. Bioassay-guided fractionation led to the isolation of these new compounds and spectroscopic analysis was utilized in their structural characterization. Two new and potent antimitotic metabolites, curacins B and C, were isolated...
Resource Type:: Dissertation
Full Text:: helpful discussions; Brian Arbogast for his mass spectral work; Roger Kohnert for NMR spectroscopy. I

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Creator:: Vulpanovici, Florina Alexandra
Abstract:: This thesis details investigations of marine cyanobacterial secondary metabolism, with emphasis on a strain of Phormidium sp. collected in Indonesia. These studies assessed the effects of nineteen putative elicitor compounds on the growth and metabolite production of five species of marine cyanobacteria, biosynthetic investigation of an intriguing secondary metabolite, phormidolide,...
Resource Type:: Dissertation
Full Text:: guidance throughout my graduate career at Oregon State University. I would also like to acknowledge Brian

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Creator:: Williamson, R. Thomas
Resource Type:: Dissertation
Full Text:: the departure of Dr. Steven J. Gould from Oregon State University. Over the past several years he

ScholarsArchive@OSU

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Oxylipins from temperate marine algae and a photoprotective sheath pigment from blue-green algae

Natural products from temperate and tropical marine algae

Novel bioactive secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

New bioactive natural products from marine algae and cyanobacteria

Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

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