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Novel icosanoids from the red marine alga Farlowia mollis

Creator:: Solem, Michele Lee
Abstract:: Farlowia mollis is a marine red alga that grows in the intertidal region along the coast of Oregon. We began studying the chemistry of this alga after a survey of Oregon seaweeds revealed possibly interesting chemistry and antimicrobial activity in its crude organic extract. Over the past three years the...
Resource Type:: Masters Thesis

Novel oxylipins and heterocycles from the Rhodophyta and Cyanophyta

Creator:: Jiang, Zhi-dong
Resource Type:: Dissertation
Full Text:: . George H. Constantine for his encouragement and cheerful times, Dr. Steven J. Gould for many good

Novel oxylipins and other bioactive metabolites from marine algae

Creator:: Nagle, Dale George
Abstract:: I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
Resource Type:: Dissertation
Full Text:: support: Dr. Philip J. Proteau, a great travel partner and friend, his commitment family, friends and to

Biosynthetic investigations of two secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Creator:: Rossi, James V.
Abstract:: Marine cyanobacteria have been shown to produce a variety of biologically active and stucturally diverse secondary metabolites. These compounds are of interest to natural products researchers mainly because of their potential application as biomedicinals, biochemical probes, and agrichemicals. The metabolic pathways utilized by the cyanobacterium Lyngbya majuscula to generate curacin...
Resource Type:: Masters Thesis
Full Text:: from the marine cyanobacterium Lyngbya majuscula AN ABSTRACT OF THE THESIS OF James Rossi for the

Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

Creator:: Yoo, Hye-Dong
Abstract:: My investigations of the natural products of marine algae have resulted in the discovery of several new secondary metabolites. Bioassay-guided fractionation led to the isolation of these new compounds and spectroscopic analysis was utilized in their structural characterization. Two new and potent antimitotic metabolites, curacins B and C, were isolated...
Resource Type:: Dissertation
Full Text:: -- -- -- -- -- -- - -- - -- -- -- -- -- -- - - -- -- -- - -- -- -- -- -- - M O D oh ha l C R S 55 V . S am ha n 14 3 10 50 1 M D IC J M a 73 64

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Creator:: Sitachitta, Namthip
Abstract:: The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
Resource Type:: Dissertation
Full Text:: . Rossi, Dr. Matthew D. Fletcher (U. ofBristol, UK) and Dr. Christine L. Willis (U. ofBristol, UK) were

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Creator:: Williamson, R. Thomas
Resource Type:: Dissertation
Full Text:: the departure of Dr. Steven J. Gould from Oregon State University. Over the past several years he

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Creator:: Milligan, Kenneth Edward
Abstract:: This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...
Resource Type:: Dissertation
Full Text:: thanks. I need to specifically mention Dr. Brian Marquez, Dr. Thomas Williamson, and Jim Rossi for their

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Creator:: Marquez, Brian L.
Abstract:: This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
Resource Type:: Dissertation
Full Text:: , B. W. J. Am. Chem. Soc. 2000, 122, 9391-9395. 19. Rossi, J. V. M.S. Thesis, Oregon State University

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: -1 245. (b) Verdier-Pinard, P.; Sitachitta, N.; Rossi, J. V.; Sackett, D. L.; Gerwick, W. H.; Hamel

ScholarsArchive@OSU

Novel icosanoids from the red marine alga Farlowia mollis

Novel oxylipins and heterocycles from the Rhodophyta and Cyanophyta

Novel oxylipins and other bioactive metabolites from marine algae

Biosynthetic investigations of two secondary metabolites from the marine cyanobacterium Lyngbya majuscula

Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

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