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Filtering by: Creator Ruehl-Fehlert%2C Christine Remove constraint Creator: Ruehl-Fehlert%2C Christine Advisor Gerwick, William H. Remove constraint Advisor: Gerwick, William H.

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  • Natural products studies of the marine cyanobacterium Lyngbya majuscula

    Creator:
    Sitachitta, Namthip
    Abstract:
    The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
    Resource Type:
    Dissertation
    Full Text:
    Institute for performing the cytotoxicity assays. I thank Dr. Christine Willis (University of Bristol

  • Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

    Creator:
    Marquez, Brian L.
    Abstract:
    This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
    Resource Type:
    Dissertation
    Full Text:
    laboratory of Dr. Christine L. Willis at the University of Bristol provided all chirally labeled substrates