Index Catalog // ScholarsArchive@OSU

Creator:: Campbell, Yan
Abstract:: The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...
Resource Type:: Dissertation
Full Text:: proteolysis of the variable C-terminal end from hCAP18 (11). It is released from the conserved N-terminal

Creator:: Guo, Chunxiao
Abstract:: Human cathelicidin antimicrobial peptide (CAMP/LL-37) is a cationic antimicrobial peptide that is widely expressed by myeloid and epithelial cells at the human-environment interface. It possesses broad spectrum antimicrobial capacity against bacteria, fungi and viruses. In addition to its direct antimicrobial activity, CAMP/LL-37 also attracts and recruits monocytes, neutrophils and other...
Resource Type:: Dissertation
Full Text:: ................................................................................................ 97 Figure 5.1. C/EBPs activate CAMP luciferase reporter

Creator:: Logan, Isabelle E.
Abstract:: Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
Resource Type:: Dissertation
Full Text:: . Jan F. Stevens provided scientific and material support. Claudia S. Maier and Jan F. Stevens

Creator:: Zhang, Yang
Abstract:: Obesity and metabolic syndrome (MetS) affect over 1.9 billion adults and 12.7 million youth in the US. If all of today’s obese American youth become obese adults, the total societal costs over their lifetime may exceed $1.1 trillion. We show that feeding rodents a high-fat diet supplemented with xanthohumol (XN)...
Resource Type:: Dissertation
Full Text:: technical assistance. Jan F. Stevens, Paul R. Blakemore, and Claudia S. Maier provided scientific and

ScholarsArchive@OSU