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Filtering by: Subject Antibiotics -- Synthesis Advisor Gould, Steven J.

Studies of the biosynthesis of Sarubicin A

Creator:

Eisenberg, Rodney L.

Abstract:

Early studies on the biosynthesis of Sarubicin A, 1, had suggested the intermediacy of the novel aromatic amino acid 6-hydroxyanthranilic acid, 17. To investigate the biosynthetic steps beyond 17, [¹³C-¹⁵N carboxamide] 6-hydroxyanthranilamide, 27a, was synthesized, and fed to fermentations of Streptomyces helicus. Incorporation of 27a into 1 provided suggestive evidence...

Resource Type:

Dissertation

Full Text:

napthoquinone antibiotic, has the 2-oxabicyclo[2.2.2]oct-5-ene structure in common with 1.6 The antibiotic G
Syntheses of labeled putative intermediates in acivicin biosynthesis

Creator:

Jiang, Nan

Resource Type:

Masters Thesis

Full Text:

of Acivicin Acivicin is an antitumor antibiotic. It also has antifungal activity. Its antibacterial
Biosyntheis of Blasticidin S : pathway and enzymes for the nucleoside formation and blastidic acid assembly

Creator:

Guo, Jincan

Resource Type:

Dissertation

Full Text:

approved: Dr. Ste Irn J. Gould Blasticidin S (BS) is an antifungal antibiotic produced by Streptomyces
Studies on naphthyridinomycin biosynthesis

Creator:

He, Weixuan

Resource Type:

Dissertation

Full Text:

revealed another compound, 8, with strong antibiotic activities as well. High resolution mass spectra and
Advanced studies of blasticidin S biosynthesis

Creator:

Zhang, Qibo

Resource Type:

Dissertation

Full Text:

S (BS, 1) is a peptidyl nucleoside antibiotic produced by Streptomyces griseochromogenes. The