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Filtering by: Creator McGrath, Daniel Advisor Greenwood, Juliet A.

Nanotoxicology to Nanotherapeutics : Prioritizing Hazard and Anticancer Efficacy of Nanomaterials using the Embryonic Zebrafish Model

Creator:

Wehmas, Leah C.

Abstract:

The numerous different types of nanomaterials and paucity of reliable in vivo information on toxicity has resulted in enduring uncertainties associated with health and safety risks, thereby slowing progress in nanotherapeutic assessment and development. This dissertation explores how the embryonic zebrafish model can be applied to prioritize commonly used nanomaterial...

Resource Type:

Dissertation
Analysis of Cancer Progression by Establishing Quantitative Assessments of Zebrafish Xenografts

Creator:

Gamble, John T.

Abstract:

The goal of this dissertation was to improve our abilities in acquiring critical in vivo data by establishing embryo-larva zebrafish as an exemplary model to quantitatively evaluate cancer progression. The living environment that encompasses a tumor has a significant effect on how cancer develops, grows and metastasizes. In order to...

Resource Type:

Dissertation

Full Text:

members Hyo Sang Jang, Martin Pearce, Jessica Phillips, Bach Nguyen, Veronica Puig Sanvicens, Daniel