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Filtering by: Creator Han, S.-C. Advisor Hagen, Tory M. Degree Name Honors Bachelor of Science (H.B.S.)

An Accumulation of Senescent Cells May Contribute to Chronic Inflammation of the Mammalian Liver

Creator:

Sugiyama, Aaron

Abstract:

The aging process is a biological phenomenon in mammals that heavily contributes to the onset of chronic diseases. While there are many theories that attempt to explain the biological onset of aging, one emerging theory involves chronic inflammation. Chronic inflammation has been previously linked to several age-related diseases and is...

Resource Type:

Honors College Thesis

Full Text:

Natl Acad Sci U S A 92, 9363–9367 (1995). 9. Doxaki, C., Kampranis, S. C., Eliopoulos, A. G
Quantification of Lipoic Acid InducedChanges in Nrf2-Mediated Stress Response

Creator:

Hobbs, Helen T.

Abstract:

As organisms age they lose the ability to respond to both exogenous and endogenous stresses, therefore placing them at a greater risk for the development of many diseases. The transcription factor Nrf2 is responsible for the induction of many oxidative stress response genes and therefore 3proteins. Additionally, Nrf2-mediated stress response...

Resource Type:

Honors College Thesis

Full Text:

for aging. J. Lab. Clin. Med. 140, 380–381 (2002). 14. Lu, S. C. Glutathione synthesis. Cell