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Filtering by: Creator Kuhl, Joseph C. Advisor Hase, Claudia C. Creator Hinnebusch, Joseph B.

Sodium/Proton Antiporter Activity is Essential for Virulence of Yersinia pestis

Creator:

Faulkner, Wyatt J., Ghosh, Amit, Minato, Yusuke, Winogrodzki, Judith, Lind, Erin, Plano, Gregory V., Hinnebusch, Joseph B., Dibrov, Pavel, and Häse, Claudia C.

Abstract:

We found that a strains of Yersinia pestis (KIM5) which lacked the nhaA gene was fully attenuated in a plague model. This gene produces a protein of the sodium-proton antiporter family which expel sodium ions from the bacterial cytoplasm in exchange for hydrogen ions, or protons, from the surrounding environment....

Resource Type:

Poster