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Filtering by: Committee Member Paulenova, Alena Advisor Higley, Kathryn Subject Radiation dosimetry

Blood-based gene expression as a biodosimetry model for neuroblastoma patients treated with ¹³¹I-mIBG

Creator:

Edmondson, David A.

Abstract:

Internal dosimetry is challenging and relies on estimates using MIRD or ICRP biokinetic models. To address this, we looked at gene expression analysis in whole blood from radiotherapy patients. Patients with relapsed or refractory neuroblastoma who received ¹³¹I-mIBG at UCSF were used to correlate internal ionizing radiation (IR) dose with...

Resource Type:

Masters Thesis