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Filtering by: Creator Fujita, Rod Remove constraint Creator: Fujita, Rod Advisor Ho, Emily Remove constraint Advisor: Ho, Emily

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  • A novel mechanism of chemoprevention by sulforaphane : inhibition of histone deacetylase

    Creator:
    Myzak, Melinda C.
    Abstract:
    Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
    Resource Type:
    Dissertation
    Full Text:
    Privacy ACKNOWLEDGEMENTS I would like to thank Rod Dashwood, who has served as a mentor in the true

  • Dietary soy and green tea in the prevention of prostate cancer

    Creator:
    Hsu, Anna
    Abstract:
    Prostate cancer risk is significantly lower in Asian countries compared to the US, which has prompted interest in the chemo-preventative action of dietary components such as soy and green tea commonly found in Asian diets, such as soy and green tea. Studies have suggested that soy isoflavones and green tea...
    Resource Type:
    Dissertation
    Full Text:
    doctoral committee members; Dr. Maret Traber, Dr. Urszula Iwaniec, Dr. Sheryl Thorburn, and Dr. Rod