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Filtering by: Creator Baio, Andrew Remove constraint Creator: Baio, Andrew Advisor Johnson, Colin P. Remove constraint Advisor: Johnson, Colin P. Committee Member Barbar, Elisar Remove constraint Committee Member: Barbar, Elisar

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  • Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

    Creator:
    Otto, Shauna C.
    Abstract:
    Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
    Resource Type:
    Dissertation
    Full Text:
    roadblocks. I also thank my graduate committee, Dr. Elisar Barbar, Dr. Patrick Reardon, Dr. Joe Baio, and Dr