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Filtering by: Dspace Collection Honors College Theses Advisor Kerkvliet, Nancy Commencement Year Unknown

The effect of TCDD on cytokine production during the progression of insulitis in NOD mice

Creator:

Pham, Tuan

Abstract:

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent immunosuppressant, and suppresses many disease models including graft-versus-host (GVH), experimental autoimmune encephalomyelitis (EAE) and a model of type 1 diabetes in non-obese diabetic (NOD) mice (1-3). In this study, we show that the inflammation of the pancreas due to insulitis is not a systemic autoimmune...

Resource Type:

Presentation