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Filtering by: Creator Goldman, Johanna A. L. Advisor Kerkvliet, Nancy I.

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Creator:

Prell, Rodney A.

Resource Type:

Dissertation

Full Text:

) demonstrated increased mortality of L. monocytogene-infected Swiss Webster mice fed a diet containing 50 ppb
T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Creator:

Dearstyne, Erica A.

Resource Type:

Dissertation

Full Text:

AN ABSTRACT OF THE DISSERTATION OF Erica A. Dearstyne for the
Development and evaluation of the mallard duck as a model to investigate the immunotoxicity of environmental chemicals

Creator:

Fowles, Jefferson R.

Resource Type:

Dissertation

Full Text:

Evaluation of the Mallard Duck as a Model to Investigate the Immunotoxicity of Environmental Chemicals
Direct effects of 2,3,7,8 tetrachlorodibenzo-p-dioxin on antigen-presenting cells and molecular signaling pathways in dendritic cells

Creator:

Ruby, Carl E.

Abstract:

In experimentally exposed mice, the environmental contaminant 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) produces significant suppression of adaptive immune responses at low doses. However, the underlying biochemical and cellular mechanisms of TCDD-induced immunotoxicity have remained elusive since the identification of these effects nearly 30 years ago. Antigen-presenting cells (APC) constitute various populations of...

Resource Type:

Dissertation

Full Text:

of adaptive immune responses, and represent a potential target of TCDD toxicity. Thus, the studies