Index Catalog // ScholarsArchive@OSU

Creator:: Talbott, Mary Catherine
Abstract:: The effect of pyridoxine (PN) supplementation on lymphocyte responsiveness was investigated in 15 elderly volunteers (aged 65-81 years) by measuring lymphocyte proliferation to T and B cell mitogens, lymphocyte subpopulations with monoclonal antibodies (T3, T4, T8) and plasma pyridoxal 5'-phosphate (PLP) concentration at pre-supplementation and after 1 and 2 months...
Resource Type:: Masters Thesis
Full Text:: 8, 1986. Title: The Effect of Vitamin B-6 Supplementation on Lymphocyte

Creator:: Deyo, James A.
Abstract:: Monocrotaline (MCT) is a member of a class of naturally occurring phytotoxins known as pyrrolizidine alkaloids (PAs). Exposure to PAs can result in liver and cardiopulmonary lesions as well as lymphoid organ atrophy. In the present study C57BI/6 (B6) mice received MCT (0-150 mg/kg/day, po) for 14 days. Overt toxicity...
Resource Type:: Dissertation
Full Text:: with identical dose response curves. This, along with data showing MCT decreased blastogenesis of B

Creator:: Prell, Rodney A.
Resource Type:: Dissertation
Full Text:: experimental design, data, and manuscripts; guidance; patience. Oughton, Julie A. Technical support; critical

Creator:: Levy, Sharon
Abstract:: In vivo generation of cytotoxic T cell activity against alloantigen is suppressed by the aromatic hydrocarbon (Ah) receptor binding 3,3',4,4',5,5'- hexachlorobiphenyl isomer (HxCB). Previous studies in this laboratory suggest that HxCB may alter early event(s) in the activation of cytotoxic T lymphocytes (CTL). Production of and response to interleukins 1...
Resource Type:: Masters Thesis
Full Text:: Thanks to Dr. Nancy Kerkvliet, Linda Steppan and Julie Brauner for sharing their knowledge, patience and

Creator:: Choi, Jin-Young, 1964
Abstract:: Exposure to TCDD suppresses the generation of immune responses through unknown mechanisms. Interestingly, TCDD enhances inflammatory responses to various stimuli. The goal of the studies presented in this thesis was to examine the role of hyperinflammation in TCDD-induced immunotoxicity. Previously we observed an increase in Mac-1⁺ cells in the spleen...
Resource Type:: Dissertation
Full Text:: , Julie Oughton who taught me flow cytometer and also helped thesis writing, and Dr. Dave Shepherd, Dr

Creator:: Shepherd, David M.
Abstract:: The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
Resource Type:: Dissertation
Full Text:: comprised the Kerkvliet laboratory. I would like to thank both Linda Steppan and Julie Oughton for all

Creator:: Dearstyne, Erica A.
Resource Type:: Dissertation
Full Text:: . A special thanks goes to Linda Steppan and Julie Oughton for all their time and patience with me

Creator:: DeKrey, Gregory K.
Resource Type:: Dissertation
Full Text:: .: Hollingshead, Nancy C.: Kerkvliet, Nancy I.: Oughton, Julie A.: Smith, Bradford B.: Technical

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