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Filtering by: Creator Hernandez, David Remove constraint Creator: Hernandez, David Advisor Kile, Molly L. Remove constraint Advisor: Kile, Molly L.

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  • In Utero Exposure to Arsenic and Mercury : Epigenome-Wide Associations and Newborn Health Outcomes

    Creator:
    Cardenas, Andres
    Abstract:
    Mercury and arsenic are known developmental toxicants and environmental exposures are ubiquitous worldwide from natural and anthropogenic sources. Prenatal exposure to both contaminants are independently associated with adverse perinatal health outcomes and latent disease risk that could be in part mediated by epigenetic reprogramming events. Fetal programming events involving DNA...
    Resource Type:
    Dissertation
    Full Text:
    manuscript. Dr. David C. Christiani conceptualized the study design, helped with the interpretation of

  • Prenatal and Early-life Metals Exposure and Immune Function in Children

    Creator:
    Welch, Barrett M.
    Abstract:
    Immune system development during prenatal and early-life periods are essential for healthy development. Environmental and nutritional factors during these periods have strong influences on immune development and can have impacts on disease susceptibility for an individual throughout adulthood. Globally, hundreds of millions of people experience elevated environmental exposure to arsenic,...
    Resource Type:
    Dissertation
    Full Text:
    birth cohort and follow-up studies used for each manuscript. Dr. David C. Christiani conceptualized

  • Environmental and Community Exposures and Children’s Infectious Diseases in Bangladesh

    Creator:
    Ahmed, Sharia M.
    Abstract:
    Under-5 mortality has decreased globally, but millions of children still die every year. In Bangladesh, respiratory infection and diarrheal disease remain leading causes of morbidity and mortality for children under-5, despite incredible progress in the past three decades. Immune system development begins in utero and continues into adulthood. Toxic environmental...
    Resource Type:
    Dissertation
    Full Text:
    protein variables and reviewed manuscript one. Dr. David C. Christiani conceptualized the study

  • Environmental Metal Exposures and Effects on Maternal and Child Health in Bangladesh

    Creator:
    Andrews, Faye V.
    Abstract:
    Bangladesh is a developing country with burdens of environmental pollution and disparities in maternal and child health. Arsenic, manganese, and lead are pervasive environmental contaminants throughout Bangladesh with major exposures through drinking water and ambient pollution. Chronic exposures to arsenic, manganese, and lead in sensitive populations such as pregnant women,...
    Resource Type:
    Dissertation
    Full Text:
    . Dr. David C. Christiani – Conceptualized the study design and reviewed each manuscript. TABLE

  • Polycyclic Aromatic Hydrocarbons (PAH) Exposure Trends, and Evidence of Adverse Health Effects in Infants and Children from Prenatal/Early-Life PAH Exposure

    Creator:
    Hudson-Hanley, Barbara A.
    Abstract:
    Polycyclic aromatic hydrocarbons (PAHs) are complex mixtures that form when organic matter is burned. Humans are primarily exposed to PAHs via air pollution from incomplete combustion of fossil fuels and biomass, such a motor vehicle exhaust, cigarette smoke, wood smoke, or industrial emissions; or via ingestion of PAHs bound to...
    Resource Type:
    Dissertation
    Full Text:
    , David Bernell, my Minor Professor, and Carolyn Aldwin, for your commitment and counsel. I’m grateful