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Filtering by: Creator Rosenthal, Yair Advisor Kioussi, Chrissa

Homeodomain Transcription Factor Pitx2 is Required for Muscle Maintenance and Energy Homeostasis

Creator:

Lattier, Vera C.

Abstract:

Skeletal muscle, the largest organ in the body in mass, is composed by 600 specialized muscles in humans with unique biochemical, physiological and metabolic identities. Skeletal muscles control body movement, locomotion, and nutrient balance. Muscle formation requires precisely orchestrated environmental signals and regulatory gene networks in time and space. Gene...

Resource Type:

Dissertation
The role of the homeodomain transcription factor Pitx2 in regulating skeletal muscle precursor migration and higher order muscle assembly

Creator:

Campbell, Adam L.

Abstract:

Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The regulatory mechanisms that control the later steps of this...

Resource Type:

Dissertation

Full Text:

. Kalcheim C, Ben-Yair R (2005) Cell rearrangements during development of the somite and its derivatives