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Filtering by: Creator Randall, Andrea Advisor Larson, Robert E. Rights Statement Copyright Not Evaluated

Hepatic mixed function oxygenase activity in rats during cholestasis following 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) treatment

Creator:

Stolzenbach, James Carlson, 1954-

Abstract:

Rats were given single i.p. injections of BCNU to investigate changes in hepatic cytochrome P-450 content and specific activity in male rats. Microsomal P-450 levels were unchanged from 6 hours to 7 days after BCNU treatment but by day 21 they had decreased 45%. Ethylmorphine N-demethylase activity (nm product x...

Resource Type:

Dissertation