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Filtering by: Contributor Gonzalez-Montiel, Gisela Advisor Loesgen, Sandra

Bioprospecting the Chemical Diversity of Plant-associated Fungi

Creator:

González-Montiel, Gisela Abigail

Abstract:

Fungi have long been used for discovery of new chemical scaffolds. In the clinical setting, the fungal natural products penicillin, statins, and cyclosporine have revolutionized medicine to treat diseases and infections. In the environment, fungal natural products have been used as herbicides, fungicides, and insecticides to protect crops, livestock, and...

Resource Type:

Masters Thesis

Full Text:

. ©Copyright by Gisela A. González-Montiel July 11, 2019 All Rights Reserved Bioprospecting
Drug Discovery from Diverse Bacteria – Bioactivity-guided Isolation of Known and New Metabolites

Creator:

Zhu, Chenxi

Abstract:

Exploring bioactive natural products has contributed largely to clinically approved drugs we have been using over the last 100 years. Especially among the anti-infective drugs, around 70% of currently used antibiotics were discovered or derived from microbial secondary metabolites, among them compounds like vancomycin, chloramphenicol, and erythromycin. Facing the unavoidable...

Resource Type:

Dissertation

Full Text:

. Birte Plitzko, Gisela González- Montiel, Mahsa Khoshbakht, and many undergraduate students. I am