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Filtering by: Has journal Forest Products Journal Remove constraint Has journal: Forest Products Journal Advisor Mahmud, Taifo Remove constraint Advisor: Mahmud, Taifo Non-Academic Affiliation Oregon State University. Honors College Remove constraint Non-Academic Affiliation: Oregon State University. Honors College

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  • Exploring Pactamycin Biosynthesis

    Creator:
    Roland, Jessica
    Abstract:
    Pactamycin, produced by the soil bacterium Streptomyces pactum, is a cytotoxic antibiotic that belongs to the aminocyclitol family of natural products. This antibiotic has shown various forms of biological activity, including antibacterial, antifungal, antimalarial, and antitumor activities. Despite its outstanding biological activity, the mode of formation of its pharmacophore (the...
    Resource Type:
    Honors College Thesis
    Full Text:
    cytotoxic antibiotic that belongs to the aminocyclitol family of natural products. This antibiotic has

  • Drug Discovery in Soil Bacteria from Unique Ecosystems of India and Indonesia

    Creator:
    Tran, Victor
    Abstract:
    Natural products isolated from bacteria can be developed into new therapeutic agents. The soil bacteria actinomycetes, specifically the Streptomyces species, are prolific producers of antibiotics. This thesis is composed of two projects which focus on novel drug discovery from soil bacteria collected from the Indonesian Black Water Ecosystem (the ICBB...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ________________________________________ Dr. Taifo Mahmud Natural products

  • Isolation and Identification of Indole Metabolites from Pseudomonas fluorescens NZI7

    Creator:
    Vergis, John M.
    Abstract:
    Pseudomonas fluorescens NZI7 was first isolated from a New Zealand mushroom farm in 2001. This Gram-negative bacteria can cause brown blotch disease in the basidiomycete mushroom Agaricus bisporus. P. fluorescens NZI7 can also repel grazing by the nematode Caenorhabditis elegans, a natural predator of P. fluorescens NZI7. Potentially implicated in...
    Resource Type:
    Honors College Thesis
    Full Text:
    would be a prenylated product. The sole presence of unprenylated indole products in the metabolic

  • Antibiotic Discovery in Soil Bacteria Isolated from Indonesian Black Water Ecosystems

    Creator:
    Lam, Phillip Westly
    Abstract:
    Soil bacteria are known to be a prolific source of bioactive compounds. They produce secondary metabolites that can be used as therapeutic agents. This investigation focused on the chemistry and biology of secondary metabolites from two soil bacteria, Streptomyces herbaricolor ICBB 9409 and Streptomyces albiflaviniger ICBB 9297, which were isolated...
    Resource Type:
    Honors College Thesis
    Full Text:
    clinically used antibiotics are natural products or natural product derivatives. They are produced by

  • Multiple Approaches to Novel Rifamycin Analogs to Combat MDR-TB

    Creator:
    Blank, Jessica A.
    Abstract:
    According to the Center for Disease Control and Prevention (CDC), in 2015 10.4 million people worldwide became infected with tuberculosis (TB) with 1.8 million TB related deaths. Tuberculosis is a bacterial infectious disease caused by Mycobacterium tuberculosis, a slow growing yet highly infectious bacterium. Among the first line of treatments...
    Resource Type:
    Honors College Thesis
    Full Text:
    rifampin, a synthetic derivative of the natural product rifamycin B. Rifampin selectively inhibits