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Filtering by: Subject Ketoconazole -- Mechanism of action Remove constraint Subject: Ketoconazole -- Mechanism of action Advisor Mahmud, Taifo Remove constraint Advisor: Mahmud, Taifo

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  • Mechanistic Studies and Catalytic Engineering of the Pseudoglycosyltransferase VldE

    Creator:
    Abuelizz, Hatem A.
    Abstract:
    This thesis describes an investigation of the molecular basis of the substrate specificity and catalytic mechanism of a unique pseudoglycosyltransferase (PsGT) enzyme, VldE. PsGTs are a newly discovered group of glycosyltransferase (GT)-like proteins that catalyze the transfer of a pseudosugar to an acceptor molecule via a C-N bond formation. This...
    Resource Type:
    Dissertation
    Full Text:
    specificity and catalytic mechanism of a unique pseudoglycosyltransferase (PsGT) enzyme, VldE. PsGTs are a