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Filtering by: Subject Time-of-flight mass spectrometry Remove constraint Subject: Time-of-flight mass spectrometry Advisor Maier, Claudia S. Remove constraint Advisor: Maier, Claudia S. Committee Member Barofsky, Doug Remove constraint Committee Member: Barofsky, Doug

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  • Tandem mass spectrometric analysis of protein and peptide adducts of lipid peroxidation-derived aldehydes

    Creator:
    Wu, Jianyong
    Abstract:
    The adduction of proteins and other biomolecules by electrophilic lipid peroxidation products such as 4-hydroxy-2-nonenal (HNE), 4-oxo-2-nonenal (ONE), malondialdehyde (MDA) or acrolein (ACR) is thought to be an initiating and/or propagating factor in the pathophysiology of several diseases such as atherosclerosis, diabetes, Alzheimer's, Parkinson's and other age-related disorders. The identification...
    Resource Type:
    Dissertation
    Full Text:
    , Brian Arbogast, Jeff Morre and the rest of the mass spectrometry group for their support. Thanks are