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Filtering by: Subject Time-of-flight mass spectrometry Advisor Maier, Claudia S. Creator Nirudodhi, Sasidhar N.

Hydrogen/deuterium exchange mass spectrometry as a technology platform for studying conformational dynamics in large protein complexes

Creator:

Nirudodhi, Sasidhar N.

Abstract:

Proteins are essential to all biological systems. Proteins participate in numerous cellular processes by interacting with other proteins, other metabolites and membranes in a dynamic environment. Studying the structural and conformational properties of proteins in the solution phase is necessary to understand their protein folding and interaction dynamics. This research...

Resource Type:

Dissertation

Full Text:

exchange mass spectrometry (HDX MS) technology for studying the conformational dynamics of large multi