Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Subject Time-of-flight mass spectrometry Advisor Maier, Claudia S. Subject Mass spectrometry

Hydrogen/deuterium exchange mass spectrometry as a technology platform for studying conformational dynamics in large protein complexes

Creator:

Nirudodhi, Sasidhar N.

Abstract:

Proteins are essential to all biological systems. Proteins participate in numerous cellular processes by interacting with other proteins, other metabolites and membranes in a dynamic environment. Studying the structural and conformational properties of proteins in the solution phase is necessary to understand their protein folding and interaction dynamics. This research...

Resource Type:

Dissertation

Full Text:

exchange mass spectrometry (HDX MS) technology for studying the conformational dynamics of large multi
Mass-spectrometric Methods for Quantitative Proteomics and Post-translational Modification Mapping

Creator:

Motorykin, Ievgen

Abstract:

Signal transduction within and between cells is at the core of biological activity in all living systems. Signaling networks are required for regulating biological functions, including growth, development and survival. Deregulation of signaling cascades has been linked to chronic and acute diseases and disorders This thesis focuses on mass spectrometry...

Resource Type:

Dissertation