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Filtering by: Alt title Sinking Tool salvage modification DR for EA #OR-014-96-04 Remove constraint Alt title: Sinking Tool salvage modification DR for EA #OR-014-96-04 Advisor Mathews, Christopher K. Remove constraint Advisor: Mathews, Christopher K.

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  • Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

    Creator:
    Bernard, Mark Aguirre
    Abstract:
    Although the Escherichia coli host has almost all of the enzymes necessary to synthesize nucleotides needed for bacteriophage T4 DNA replication, phage genes expressed early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host DNA. Eight early enzymes and two host enzymes comprise the...
    Resource Type:
    Dissertation
    Full Text:
    early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host

  • Deoxyribonucleotides as determinants of DNA replication fidelity in bacteriophage T4

    Creator:
    Sargent, Roy Geoffrey
    Abstract:
    Imbalanced deoxyribonucleoside triphosphate (dNTP) pools are mutagenic for DNA synthesis in both intact cells and cell-free replication systems. Almost certainly, such mutagenesis involves competition between correctly and incorrectly base-paired precursors at replication sites. However, there are certain differences between the intact cell and cell-free systems that do not always allow...
    Resource Type:
    Dissertation
    Full Text:
    for Roy Geoffrey Sargent Acknowledgments I want to thank Dr. Christopher K. Mathews for the