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Filtering by: Creator Loughborough, W. Karl Remove constraint Creator: Loughborough, W. Karl Advisor Mcguire, Joseph Remove constraint Advisor: Mcguire, Joseph Creator Auxier, Julie A. Remove constraint Creator: Auxier, Julie A.

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  • Quantification of fibrinogen adsorption to nisin-loaded polyethylene oxide layers

    Creator:
    Auxier, Julie A.
    Abstract:
    Antimicrobial coatings used to reduce the risk of infection caused by tissue-contacting medical devices must address specific biocompatibility requirements including prevention of thrombosis and rise of bacterial resistance. An antimicrobial-loaded poly(ethylene-oxide) (PEO) coating has been tentatively shown to be non-fouling with sustained antimicrobial activity. However, the presence of the antimicrobial,...
    Resource Type:
    Honors College Thesis
    Full Text:
    also in my overall professional development. I also extend my gratification to Dr. Karl Schilke for

  • Retention of protein repulsive character and antimicrobial activity of PEO brush layers following nisin entrapment

    Creator:
    Auxier, Julie A.
    Abstract:
    Nisin, an amphiphilic, antimicrobial peptide, has been shown to integrate into the hydrophobic inner region of poly(ethylene oxide) (PEO) brush layers; however, the presence of integrated nisin may compromise the protein repulsive character of the PEO layer. In particular, the introduction of fibrinogen to nisin-loaded brush layers has been observed...
    Resource Type:
    Masters Thesis
    Full Text:
    all his guidance and support. I also extend my sincere gratitude to Dr. Karl Schilke, who I will