Search Constraints

Start Over
Filtering by: Creator Cannon, Joseph R. Remove constraint Creator: Cannon, Joseph R. Advisor Mcguire, Joseph Remove constraint Advisor: Mcguire, Joseph Degree Field Bioengineering Remove constraint Degree Field: Bioengineering

Search Results

  • Characterization and application of PEO-containing triblock copolymer surfactants

    Creator:
    Snider, Joshua L.
    Abstract:
    The action of pendant, polyethylene oxide (PEO) brush layers as nonfouling coatings for biomedical materials is well understood. However progress toward clinical application of stable, high density PEO coatings has historically been impeded by the lack of cost effective, noninvasive methods for their preparation. Triblock polymers featuring a hydrophobic, polypropylene...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ______________________________________________________________ Joseph McGuire The action of pendant, polyethylene oxide (PEO) brush layers as nonfouling

  • Molecular origins of peptide entrapment within polyethylene oxide brush layers

    Creator:
    Lampi, Marsha C.
    Abstract:
    Effective surface coatings for tissue-contacting medical devices should prevent both biofilm formation and infection. One method to achieve this aim is protein repellant polyethylene oxide (PEO) brush coatings loaded with antimicrobials. Previous research has demonstrated that the antimicrobial nisin adsorbs to PEO brush layers in multi-layer amounts and suggests that...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Abstract approved: ________________________________________________ Dr. Joseph

  • The Role of Syndecan-1 in Arterial Mechanotransduction

    Creator:
    Steyer, Benjamin G.
    Abstract:
    Hemodynamic forces regulate vascular homeostasis and arterial structure through mechanical stimuli by a process called mechanotransduction. Cellular response to mechanical forces involves coordination between cell surface receptors and intracellular signaling pathways. While previous work has focused on the role of integrin receptors in mechanotransduction, little is known about the role...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ______________________________________________________ Dr. Joseph McGuire Hemodynamic forces regulate vascular homeostasis and arterial structure

  • The Role of Syndecan-1 in Arterial Mechanotransduction.

    Creator:
    Steyer, Benjamin G.
    Abstract:
    Hemodynamic forces regulate vascular homeostasis and arterial structure through mechanical stimuli by a process called mechanotransduction. Cellular response to mechanical forces involves coordination between cell surface receptors and intracellular signaling pathways. While previous work has focused on the role of integrin receptors in mechanotransduction, little is known about the role...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ______________________________________________________ Dr. Joseph McGuire Hemodynamic forces regulate vascular homeostasis and arterial structure

  • Quantification of fibrinogen adsorption to nisin-loaded polyethylene oxide layers

    Creator:
    Auxier, Julie A.
    Abstract:
    Antimicrobial coatings used to reduce the risk of infection caused by tissue-contacting medical devices must address specific biocompatibility requirements including prevention of thrombosis and rise of bacterial resistance. An antimicrobial-loaded poly(ethylene-oxide) (PEO) coating has been tentatively shown to be non-fouling with sustained antimicrobial activity. However, the presence of the antimicrobial,...
    Resource Type:
    Honors College Thesis
    Full Text:
    layers. Abstract approved: _______________________________________________________ Joseph

  • Functionalization of Surfaces with Nisin in a Polyethylene Oxide Brush Layer

    Creator:
    Ryder, Matthew P.
    Abstract:
    Infections in hospitals account for over 100,000 deaths per year. These infections occur at the hospital from complications following bacterial adhesion to intravenous catheters, coronary stents and other implanted devices. Another common problem is protein adsorption to the surface of the device and subsequent blood clotting. Methods for combating these...
    Resource Type:
    Honors College Thesis
    Full Text:
    :  ____________________________________________________              Joseph McGuire    Infections in hospitals account for over 100,000 deaths per year