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Filtering by: Creator Henning, Julie A. Advisor Mcguire, Joseph

Retention of protein repulsive character and antimicrobial activity of PEO brush layers following nisin entrapment

Creator:

Auxier, Julie A.

Abstract:

Nisin, an amphiphilic, antimicrobial peptide, has been shown to integrate into the hydrophobic inner region of poly(ethylene oxide) (PEO) brush layers; however, the presence of integrated nisin may compromise the protein repulsive character of the PEO layer. In particular, the introduction of fibrinogen to nisin-loaded brush layers has been observed...

Resource Type:

Masters Thesis

Full Text:

the presence of other proteins. ©Copyright by Julie A
Quantification of fibrinogen adsorption to nisin-loaded polyethylene oxide layers

Creator:

Auxier, Julie A.

Abstract:

Antimicrobial coatings used to reduce the risk of infection caused by tissue-contacting medical devices must address specific biocompatibility requirements including prevention of thrombosis and rise of bacterial resistance. An antimicrobial-loaded poly(ethylene-oxide) (PEO) coating has been tentatively shown to be non-fouling with sustained antimicrobial activity. However, the presence of the antimicrobial,...

Resource Type:

Honors College Thesis

Full Text:

Julie A. Auxier for the degree of Honors Baccalaureate of Science in Bioengineering presented on June