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Filtering by: Creator Sellers, Jason R. V. Advisor Mehl, Ryan A. Degree Level Bachelor's

Selection of an Orthogonal tRNA Synthetase for Trifluoromethyl-phenylalanine in Methanomethylophilus Alvus System

Creator:

Eyberg, Daniel R.

Abstract:

Genetic code expansion is a technology that allows for site-specific incorporation of noncanonical amino acids into recombinant proteins at amber stop codons using engineered translational machinery. The technology allows for expanded study into proteins, derived from the integration of novel chemical functions found in noncanonical amino acids, such as fluorescence,...

Resource Type:

Honors College Thesis

Full Text:

, M. A.; Tan, Z.; Cornish, V. W. Genetic Code Expansion: A Brief History and Perspective
Controlled Orientation of Engineered Carbonic Anhydrase on a Surface : A Model for Protein Immobilization for Biosensors and Biomaterials

Creator:

Brown, Wesley

Abstract:

Current protein immobilization techniques lack defined control over protein orientation. Protein orientation is important for making biosensors and biomaterials that are sensitive and efficient and can be crucial for designing some devices such as immunosensors or direct electron transferring biocells. A new method of protein immobilization is proposed that takes...

Resource Type:

Honors College Thesis