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Filtering by: Advisor Morgun, Andrey Decade 2010-2019

Identification of Cervical Cancer Key Regulators using Network Biology Approach

Creator:

Vyshenska, Dariia

Abstract:

Cervical cancer is the fourth most common cancer in women worldwide with human papillomavirus (HPV) being the main cause of the disease. Currently available treatment methods are limited and emphasize the need for discovery of new therapies that improve patient outcome. Chromosomal amplifications have been identified as a source of...

Resource Type:

Dissertation
Metagenomics Analysis Reveal Host-Microbe Interactions in Cervical Cancer

Creator:

Lam, Khiem C.

Abstract:

Cervical cancer is the fourth most common cancer in women worldwide. Recently it has been shown that microbiota play a role in some types of cancer. Therefore, to understand whether microbes contribute in any way to the development and progress of cervical cancer, we investigated the cervical microbiome via analysis...

Resource Type:

Presentation and Honors College Thesis
Unexpected links reflect the noise in networks

Creator:

Yambartsev, Anatoly, Perlin, Michael A., Kovcehgov, Yevgeniy, Shulzhenko, Natalia, Mine, Karina L., Dong, Xiaoxi, and Morgun, Andrey

Abstract:

Gene regulatory networks are commonly used for modeling biological processes and revealing underlying molecular mechanisms. The reconstruction of gene regulatory networks from observational data is a challenging task, especially considering the large number of players (e.g. genes) involved and the small number of biological replicates available for analysis. Herein, we...

Resource Type:

Article