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Filtering by: Subject Phenylbutazone -- Physiological effect Advisor Murray, Thomas F. Degree Name Master of Science (M.S.)

Purine nucleotide-induced seizures in rat prepiriform cortex

Creator:

Zhao, Xiaoqin S.

Resource Type:

Masters Thesis

Full Text:

anticonvulsant effect of 2 methylthio-ATP is therefore likely to be due to its breakdown to 2-methylthio
Adenosine analogs suppress seizures induced by bicuculline methiodide in the rat prepiriform cortex

Creator:

Zhang, Ge

Abstract:

Although considerable experimental evidence suggests that endogenous adenosine may function as a modulator of neuronal activity in the etiology or control of seizures, the neuroanatomical and neurochemical basis for the anticonvulsant actions of adenosine have not been well established. A discrete brain region of possible fundamental importance to epileptogenisis within...

Resource Type:

Masters Thesis

Full Text:

rank order potency, degree of stereoselectivity for R-PIA vs S-PIA and lack of anticonvulsant effect