The semi-parametric approach to the analysis of proportional hazards survival data
is relatively new, having been initiated in 1972 by Sir David Cox, who restricted its use
to hypothesis tests and confidence intervals for fixed effects in a regression setting.
Practitioners have begun to diversify applications of this model, constructing...
Randomized trials are the gold standard for the clinical assessment of a new treatment
compared to a placebo or standard of care. Often in clinical trials, patients are
accrued sequentially rather than all at once. Thus, the data from such a trial becomes
available sequentially to the researcher. Monitoring and...
Density dependence is an ecological concept concerning the mechanisms of change in the size of a population. The inability to census ecological populations confounds approaches to identify and quantify the level of density dependence. Statistical tests which ignore the presence of measurement error tend to result in misspeci fied type...