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Filtering by: Creator Dahl, Fredrick Henry Advisor Parks, Leo W. Degree Name Doctor of Philosophy (Ph.D.)

Defining roles for sterols in Saccharomyces cerevisiae : characterization of bulk membrane and high specificity sparking functions

Creator:

Rodriguez, Russell John

Abstract:

The ability of cholestanol to support growth of yeast sterol auxotrophs has been examined. Growth on this stanol was precluded unless minute quantities of ergosterol were available, a phenomenon designated sparking. The low levels of ergosterol were insufficient to support growth alone. The data indicate that cholestanol is fulfilling a...

Resource Type:

Dissertation

Full Text:

John Rodriguez ACKNOWLEDGEMENTS I wish to gratefully thank Dr. Henry W. Kircher and Dr. Eliahu
Coordinated regulation of plasma membrane lipids in Saccharomyces cerevisiae

Creator:

Low, Christopher S. F.

Abstract:

Plasma membranes isolated from a yeast sterol auxotroph (RD5-R) grown on 1,5, and 15 pg m1⁻¹ exogenous concentrations of sterol showed no discontinuity in plots of steady-state fluorescence anisotropy. Liposomes constructed from phospholipid and sterol extracted from RD5-R grown on different sterols indicated exogenously supplied sterol modulated cellular phospholipids such...

Resource Type:

Dissertation