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Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: , PU.1 [27] 2010 M. Marullo, M. Valenza, C. Mariotti et al. NRSF [28] 2011 P. Li, J. Wong, C

Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: , PU.1 [27] 2010 M. Marullo, M. Valenza, C. Mariotti et al. NRSF [28] 2011 P. Li, J. Wong, C

Creator:: Kashyap, Amita
Abstract:: Long noncoding RNAs (lncRNAs) are RNA molecules that are at least 200 nucleotides long and do not encode proteins. lncRNAs have roles in gene regulation, chromatin epigenetics, and molecular scaffolding. In light of mounting evidence implicating species-specific noncoding RNAs and gene regulatory mechanisms in species adaptations, it is reasonable to...
Resource Type:: Honors College Thesis
Full Text:: ) • Oxidative Stress (mouse) Amaral, P. P., Dinger, M. E. & Mattick, J. S. Non-coding RNAs in homeostasis

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