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Filtering by: Creator Gregory, Sarah Advisor Ramsey, Stephen A.

Analytical Methods for Improving Causal Inference

Creator:

Sinha, Meghamala

Abstract:

Causal inference is an important analytical tool to bridge the gap between prediction and decision-making. However, learning a causal network solely from data is a challenging task. In this work, various techniques have been explored for a better and improved causal network learning from data. Firstly, the problem of learning...

Resource Type:

Dissertation
Computational Elucidation of the Regulatory SNPs in the Non-Coding Regions of the Human Genome

Creator:

Yao, Yao

Abstract:

We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...

Resource Type:

Dissertation
Machine Learning for Precision Medicine: Application to Cancer Chemotherapy Response Prediction and Wound Healing Status Assessment

Creator:

Wei, Qi

Abstract:

Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...

Resource Type:

Dissertation