Index Catalog // ScholarsArchive@OSU

RNA and DNA aptamers as affinity stationary phases for liquid chromatography and capillary electrochromatography

Creator:: Clark, Stacey L.
Abstract:: Due to a number of disadvantages associated with the use of antibodies as affinity stationary phases, researchers have recently began to explore the use of RNA and DNA aptamers for use as affinity stationary phases. These molecules have been shown to be a viable choice for applications in many methods...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Stacey L. Clark for the

Design, fabrication and application of a microfluidic nanofiltration module for separation and purification of macromolecules and nanoparticles

Creator:: Rundel, Jack T.
Abstract:: A microfluidic nanofiltration module has been designed, fabricated and applied to the continuous-flow, pressure-driven, post-synthetic purification of macromolecules and nanoparticles via diafiltration using a commercially available organic solvent resistant nanofiltration membrane, STARMEM 122. This module will readily interface with other microscale components within a "nanofactory" for the rapid synthesis, purification...
Resource Type:: Dissertation
Full Text:: concentrations. Stable permeances of 2 L m-2 h-1 bar-1 were also observed, comparable to those reported in the

Organic-solvent resistant ultrafiltration and nanofiltration membrane modules for separation and purification of nanoparticles

Creator:: Kim, Taehyeong
Abstract:: The intriguing size- and shape dependent properties of nanoparticles have garnered recent attention in many science and engineering areas. When the particle size is in the nanometer size range, the material exhibits very different properties such as surface plasmon resonance (of gold nanoparticles) and superparamagnetism (of iron oxide nanoparticles). The...
Resource Type:: Dissertation
Full Text:: . Chem. 73 (2001) 5758-5761. [9] X. Sun, S.M. Tabakman, W. Seo, L. Zhang, G. Zhang, S. Sherlock, L

Carbon Nanodots as Biolabels for Fluorescence Immunoassays

Creator:: Wu, Yuanyuan
Abstract:: There has been a tremendous growth in interest in carbon nanodots (C-dots) in the past several years. As a nascent nanomaterial, C-dots have shown great promise in applications that benefit from their superior water dispersibility, low toxicity, non-blinking fluorescent output, chemical and biological compatibility, ease of functionalization and resistance to...
Resource Type:: Dissertation
Full Text:: thank my thesis committee, Dr. Christopher. M. Beaudry, Dr. Claudia Maier, Dr. Joseph. W. Nibler, Dr

Micro total analysis system for in-situ and autonomous spectrophotometric monitoring of iron in groundwater

Creator:: Koch, Corey R.
Abstract:: We have developed a compact micro total analysis system (μTAS) to serve as a platform for in-situ spectrophotometric water quality monitoring. Individual fluidic, optical, and electrical components were designed, developed, and characterized. These components were combined in both an integrated (single lithographic “chip-based” platform) and a modular manner. The microfluidic...
Resource Type:: Dissertation
Full Text:: 3.4 x 10-3 AU/µM; 10% difference for an environmental sample). For the complete µTAS, the detection

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Creator:: Hutanu, Daniela
Abstract:: The emerging field of nanotechnology strictly requires the micro-scaling of the available separation technology and the design of novel devices for separations of molecules of interest. The separation of proteins and nanoparticles is challenging due to their relatively large size, non-specific adherence to surfaces and instability in many solvents. This...
Resource Type:: Dissertation
Full Text:: for their help, friendship and advice: Bin Cao, Esha Chatterjee, Stacey L. Clark, Angela Doneanu

Gold Nanoparticles as Thiophenol Detection Probes

Creator:: Pond, Emily
Abstract:: The development of simple, rapid, and sensitive methods for thiophenol detection is of great importance in various fields, including environmental monitoring and food quality. Here, we present a novel approach for the colorimetric detection of thiophenols using gold nanoparticles (AuNPs) as the sensing platform. AuNPs aggregate in the presence of...
Resource Type:: Honors College Thesis
Full Text:: ) IMMEDIATELY FOLLOWING THE ADDITION OF 3ML OF 1% (W/W) SODIUM CITRATE SOLUTION. THE COMBINED SOLUTION BECAME

Detection techniques for biomolecules using semi-conductor nanocrystals and magnetic beads as labels

Creator:: Chatterjee, Esha
Abstract:: Continued interest in the development of miniaturized and portable analytical platforms necessitates the exploration of sensitive methods for the detection of trace analytes. Nanomaterials, on account of their unique physical and chemical properties, are not only able to overcome many limitations of traditional detection reagents but also enable the exploration...
Resource Type:: Dissertation
Full Text:: 585-CT , QD-Au (1:1) without thrombin and QD-Au with 160 nM thrombin

Polylcaprolactone-Based Microfluidic Devices : Fabrication Methods and Applications in Low-Cost Analytical Devices

Creator:: Heist, Christopher A.
Abstract:: The overall concept of reducing laboratory operations to a scale that fits on a single microfluidic chip has been an attractive area of research over the last several decades. Despite a surge in research, few commercial success stories have been written. Lab-on-a-chip technologies have the capability to be cost effective...
Resource Type:: Dissertation

Potential Additive-Manufacturing of Ablative Thermal Protection Systems

Creator:: Hazell, Kenya K.
Abstract:: Electrodeposition is a versatile polymer deposition technique to create nano-microscale materials using an electrical field generated from a charged droplet of solution and a grounded collector. Electrospinning or electrospraying can occur during electrodeposition, leading to the creation of nanofibers or bead-like materials depending on the process parameters. Photopolymerization of the...
Resource Type:: Dissertation
Full Text:: < 0.7 g/cm3 Heating > 100 W/cm2 Char yield > 50 % Thermal conductivity Low Coefficient of

ScholarsArchive@OSU

RNA and DNA aptamers as affinity stationary phases for liquid chromatography and capillary electrochromatography

Design, fabrication and application of a microfluidic nanofiltration module for separation and purification of macromolecules and nanoparticles

Organic-solvent resistant ultrafiltration and nanofiltration membrane modules for separation and purification of nanoparticles

Carbon Nanodots as Biolabels for Fluorescence Immunoassays

Micro total analysis system for in-situ and autonomous spectrophotometric monitoring of iron in groundwater

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Gold Nanoparticles as Thiophenol Detection Probes

Detection techniques for biomolecules using semi-conductor nanocrystals and magnetic beads as labels

Polylcaprolactone-Based Microfluidic Devices : Fabrication Methods and Applications in Low-Cost Analytical Devices

Potential Additive-Manufacturing of Ablative Thermal Protection Systems

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