Index Catalog // ScholarsArchive@OSU

From electrophoresis to dielectrophoresis: designing, fabricating, and evaluating an electroformed ratchet type microfluidic dielectrophoresis device

Creator:: Gonzalez, Carlos F.
Abstract:: Dielectrophoresis (DEP) is a separation method in which a non-uniform electric field is used to induce a dipole moment in a suspended particle. If the polarization of the particle is greater than that of the suspending medium, the particle will move towards the region of higher field strength (positive DEP);...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Carlos F. Gonzalez for the degree of Doctor of Philosophy in Chemistry presented on

Polylcaprolactone-Based Microfluidic Devices : Fabrication Methods and Applications in Low-Cost Analytical Devices

Creator:: Heist, Christopher A.
Abstract:: The overall concept of reducing laboratory operations to a scale that fits on a single microfluidic chip has been an attractive area of research over the last several decades. Despite a surge in research, few commercial success stories have been written. Lab-on-a-chip technologies have the capability to be cost effective...
Resource Type:: Dissertation
Full Text:: of properties of common microfluidic device polymers. [6] Name Density (g/cm3) Tg (˚C) Heat

Magnetic particles for selective extraction of trace analytes in microfluidic devices

Creator:: Tennico, Yolanda H.
Abstract:: The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
Resource Type:: Dissertation
Full Text:: work with: Corey Koch, Jack Rundel, and Carlos Gonzalez. I would like to acknowledge and thank my

Detection techniques for biomolecules using semi-conductor nanocrystals and magnetic beads as labels

Creator:: Chatterjee, Esha
Abstract:: Continued interest in the development of miniaturized and portable analytical platforms necessitates the exploration of sensitive methods for the detection of trace analytes. Nanomaterials, on account of their unique physical and chemical properties, are not only able to overcome many limitations of traditional detection reagents but also enable the exploration...
Resource Type:: Dissertation

Electrospray Deposition of Discrete Nanoparticles: Studies on Pulsed-Field Electrospray and Analytical Applications

Creator:: Kremer, Matthew H.
Abstract:: Electrospinning and electrospray are both nano-scale material fabrication techniques, based on related phenomena of electrically charged fluid spray from a droplet of liquid. Material is dissolved in liquid, then a spray is generated by applying a high voltage, creating an electric field, between the fluid dispensing capillary and a grounded...
Resource Type:: Masters Thesis

Quantification of Propofol in Blood Plasma and its Application to Future Clinical Research in Anesthesiology and Perioperative Medicine

Creator:: Bemis, David J.
Abstract:: High Performance Liquid Chromatography-Mass Spectrometry coupled with filtration, centrifugation, and other common sample preparation techniques offers a rapid and robust method for separating and quantifying propofol, a commonly used anesthetic, from human blood and its synthetic analogs. Method development is important for not only optimizing separation and quantification for a...
Resource Type:: Honors College Thesis

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Creator:: Hutanu, Daniela
Abstract:: The emerging field of nanotechnology strictly requires the micro-scaling of the available separation technology and the design of novel devices for separations of molecules of interest. The separation of proteins and nanoparticles is challenging due to their relatively large size, non-specific adherence to surfaces and instability in many solvents. This...
Resource Type:: Dissertation
Full Text:: …………………………..……………...6 3. Illustration of the DNA aptamer molecule containing two G-quartets………….31 4. Reaction

Monolithic sorbents for microscale separations

Creator:: Doneanu, Angela
Abstract:: Over the last decade, the miniaturization of analytical systems has become an increasingly important and interesting research area. Miniaturized systems offer many advantages, including reduced reagent and sample consumption, shorter analysis times, portability and disposability. This dissertation describes novel approaches in this direction, focusing on two areas: the miniaturization of...
Resource Type:: Dissertation
Full Text:: of this research: Gabriela Chirica, Patrick Vallano, Stacey Clark, Carlos Gonzalez, Jack Rundel

Laser patterned porous-media microfluidic analytical devices : fabrication methods and applications in bioassays

Creator:: Sumantakul, Saichon
Abstract:: The concept of reducing laboratory operations into microfluidic devices has been an attractive area of research for several decades. Due to several advantages of porous-media microfluidic devices including low mass, portability, power-free fluid transport, and the ability to store dried reagents in the porous structures, these devices show great promise...
Resource Type:: Dissertation
Full Text:: ………………………………………………………………….. Figure 2.13 Rabbit immunoglobulin G assay on nitrocellulose and commercial plastic well plates

Micro total analysis system for in-situ and autonomous spectrophotometric monitoring of iron in groundwater

Creator:: Koch, Corey R.
Abstract:: We have developed a compact micro total analysis system (μTAS) to serve as a platform for in-situ spectrophotometric water quality monitoring. Individual fluidic, optical, and electrical components were designed, developed, and characterized. These components were combined in both an integrated (single lithographic “chip-based” platform) and a modular manner. The microfluidic...
Resource Type:: Dissertation
Full Text:: instrumentation. Carlos Gonzalez, Paul Newhouse, my family, and my wife, Defne Cakin Koch, for their support

ScholarsArchive@OSU

From electrophoresis to dielectrophoresis: designing, fabricating, and evaluating an electroformed ratchet type microfluidic dielectrophoresis device

Polylcaprolactone-Based Microfluidic Devices : Fabrication Methods and Applications in Low-Cost Analytical Devices

Magnetic particles for selective extraction of trace analytes in microfluidic devices

Detection techniques for biomolecules using semi-conductor nanocrystals and magnetic beads as labels

Electrospray Deposition of Discrete Nanoparticles: Studies on Pulsed-Field Electrospray and Analytical Applications

Quantification of Propofol in Blood Plasma and its Application to Future Clinical Research in Anesthesiology and Perioperative Medicine

Synthesis and characterization of novel stationary phases for small scale liquid chromatographic separations of proteins and nanoparticles

Monolithic sorbents for microscale separations

Laser patterned porous-media microfluidic analytical devices : fabrication methods and applications in bioassays

Micro total analysis system for in-situ and autonomous spectrophotometric monitoring of iron in groundwater

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