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Filtering by: Creator Oros, Daniel R. Remove constraint Creator: Oros, Daniel R. Advisor Rockey, Daniel D. Remove constraint Advisor: Rockey, Daniel D.

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  • Genetic variation of Renibacterium salmoninarum genes in infected salmonids

    Creator:
    Burnett, Jeffrey R.
    Abstract:
    Renibacterium salmoninarum is the causative agent of bacterial kidney disease in both wild and farmed salmonid species worldwide. The genome of this pathogen has significant synteny to the ubiquitous, soil-dwelling Arthrobacter spp. though it is 1.9 Mb smaller, suggesting that reductive evolution has occurred. Recently, our group finished sequencing and...
    Resource Type:
    Undergraduate Thesis and Presentation

  • Growth and development of tetracycline resistant Chlamydia suis

    Creator:
    Lenart, Jennifer
    Abstract:
    Tetracycline is a front line antibiotic for the treatment of chlamydial infections in both humans and animals, and the emergence of tetracycline resistant (tet[superscript R]) Chlamydia is of significant clinical importance. Recently, several tet[superscript R] chlamydial strains have been isolated from swine (Sus scrofa) raised in production facilities in Nebraska....
    Resource Type:
    Masters Thesis
    Full Text:
    suis Abstract Approved: Daniel D. Rockey Tetracycline is a front line antibiotic for the treatment

  • PCR-based Sequencing System across Chlamydia trachomatis

    Creator:
    Roetcisoender, Jake
    Abstract:
    Chlamydia trachomatis is an obligate intracellular pathogen that affects millions of people worldwide via ocular or reproductive tract infection. Despite obvious differences in site of infection, there has been shown to be high levels of sequence conservation across C. trachomatis. This high level of sequence conservation is hindered with a...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Daniel Rockey Chlamydia trachomatis is an obligate intracellular pathogen that

  • Chlamydiae under stress : environmental conditions influence the production and localization of chlamydial antigens

    Creator:
    Brown, Wendy J.
    Abstract:
    Chlamydiae are obligate intracellular pathogens that cause several serious conditions within the human host. Many of the symptoms associated with infection are thought to stem from the development of aberrant, or persistent, chlamydiae. Factors leading to chlamydial persistence include deprivation of amino acids, the release of certain cellular factors, or...
    Resource Type:
    Dissertation
    Full Text:
    : Daniel D. Chlamydiae are obligate intracellular pathogens that cause several serious conditions within

  • Genetic variation of chlamydial Inc proteins

    Creator:
    Viratyosin, Wasna
    Abstract:
    Genomic analysis is a new approach for the characterization and investigation of novel genes, gene clusters, the function of uncharacterized proteins, and genetic diversity in microorganisms. These approaches are important for the study of chlamydiae, a system in which several genomes have been sequenced but in which techniques for genetic...
    Resource Type:
    Dissertation
    Full Text:
    Chlamydial Inc Proteins Abstract approved: Daniel D. Genomic analysis is a new approach for the

  • Integration of Amino Acid Sequence and Alphafold2 Structural Predictions for Chlamydia trachomatis Polymorphic Membrane Proteins

    Creator:
    DeBrine, Abigail
    Abstract:
    Chlamydia trachomatis is an obligate intracellular bacterium that causes diseases of the eye and urogenital tract in humans. It is the cause of the sexual transmitted infection (STI) chlamydia, the most prevalent STI worldwide, and the ocular disease trachoma, the leading cause of infectious blindness. To date there is no...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ________________________________________ Daniel D. Rockey Chlamydia trachomatis is an obligate intracellular bacterium that causes

  • Inclusion Fusion and Genetic Recombination: Bridging the Gap Between the Chlamydiae

    Creator:
    Garvin, Lotisha E.
    Abstract:
    Chlamydia is an obligate intracellular bacterial pathogen that causes a variety of disease in animals and humans worldwide. Veterinary chlamydial pathogens can lead to chronic infections and serious consequences that result in millions of dollars of losses in animals and resources in the agricultural industry in countries that rear ruminants....
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: Daniel D. Rockey

  • Using Culture-independent Genomics as a Means for Understanding Chlamydial Biology

    Creator:
    Putman, Timothy E.
    Abstract:
    The chlamydiae are a family of obligate intracellular bacteria that have a unique bi-phasic developmental cycle, unique cellular properties, and a unique set of challenges to studying its biology. While genetic manipulation is becoming routine in Chlamydia, there are significant challenges to working with this intracellular parasite. The body of...
    Resource Type:
    Dissertation
    Full Text:
     approved:  ______________________________________________________   Daniel  D.  Rockey

  • Polymorphic Membrane Protein-13G Expression Variation Demonstrated between Chlamydia abortus Culture Conditions and Strains

    Creator:
    Khan, Emaan M.
    Abstract:
    Chlamydiae encode a family of proteins named the polymorphic membrane proteins, or Pmps, whose role in infection and pathogenesis is unclear. The Rockey Laboratory is studying polymorphic membrane protein expression in Chlamydia abortus, a zoonotic pathogen that causes abortions in ewes. C. abortus contains 18 pmp genes, some of which...
    Resource Type:
    Honors College Thesis
    Full Text:
    Abstract approved: _____________________________________________________ Daniel Rockey Chlamydiae

  • Chromosomal Recombination Targets in Chlamydial Lateral Gene Transfer In Vitro

    Creator:
    Kim, Debbie Blue
    Abstract:
    Background: Lateral gene transfer (LGT) among C. trachomatis strains is common, both in isolates generated in the laboratory and those examined directly from patients. This is a challenging concept because there are very few examples of recent acquisition of foreign DNA by Chlamydia spp. There is no understanding of the...
    Resource Type:
    Honors College Thesis
    Full Text:
    Daniel D. Rockey Background: Lateral gene transfer (LGT) among C. trachomatis strains is common