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Filtering by: Alternative title ssim EC 768 Advisor Schimerlik, Michael I.

Characterization of neuronal nitric-oxide synthase reductase activity

Creator:

Wolthers, Kirsten R.

Abstract:

During catalysis the flavoprotein domain of neuronal nitric-oxide synthase (nNOS) shuttles NADPH-derived reducing equivalents from FAD to FMN and then to the P450-heme enabling heme-based oxygen activation and subsequent NO-synthesis. The binding of Ca²⁺-activated calmodulin (Ca²⁺-CaM) to nNOS alleviates inhibition of flavin mediated electron transfer within the diflavin domain, which...

Resource Type:

Dissertation

Full Text:

isozymes, the nitric-oxide synthases (NOS; EC 1.14.13.39), catalyze NO biosynthesis via the five-electron
Expression and G protein coupling of the M2 muscarinic acetylcholine receptor in Sf9 insect cells

Creator:

Mosser, Valerie A.

Resource Type:

Dissertation
Site-directed mutagenesis of the m2 muscarinic acetylcholine receptor

Creator:

Vogel, Walter Kevin

Resource Type:

Dissertation
Rapid kinetic studies of thymidylate synthase

Creator:

Mittelstaedt, Denice

Resource Type:

Dissertation

Full Text:

25° 768 ± 371 610 ± 400 19.0 21.5 t 3.2 30° dUMP 233 ± 15 81.3 ± 18 0.9 2.5 t 0.7 10° 188 t 81 62