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Filtering by: Creator Garza-Gil, M. Dolores Advisor Schimerlik, Michael I.

Characterization of neuronal nitric-oxide synthase reductase activity

Creator:

Wolthers, Kirsten R.

Abstract:

During catalysis the flavoprotein domain of neuronal nitric-oxide synthase (nNOS) shuttles NADPH-derived reducing equivalents from FAD to FMN and then to the P450-heme enabling heme-based oxygen activation and subsequent NO-synthesis. The binding of Ca²⁺-activated calmodulin (Ca²⁺-CaM) to nNOS alleviates inhibition of flavin mediated electron transfer within the diflavin domain, which...

Resource Type:

Dissertation
Ligand binding to the muscarinic receptor : equilibrium and kinetic studies

Creator:

Hirschberg, Birgit T.

Resource Type:

Dissertation

Full Text:

based on detailed kinetic studies of binding of the agonist oxotremorine M. Kinetic experiments
Site-directed mutagenesis of the m2 muscarinic acetylcholine receptor

Creator:

Vogel, Walter Kevin

Resource Type:

Dissertation

Full Text:

, David M. Sheehan, Kirsten Wolthers, and Anne Zimmerman for valuable assistance. I would like to
Muscarinic receptor-effector coupling in Chinese hamster ovary cells

Creator:

Bulseco, Dylan A.

Resource Type:

Dissertation

Full Text:

glutamate, oxotremorine M-mediated coupling to phosphatidyl inositol (PI) hydrolysis resulted in responses
Expression and G protein coupling of the M2 muscarinic acetylcholine receptor in Sf9 insect cells

Creator:

Mosser, Valerie A.

Resource Type:

Dissertation

Full Text:

sensitive Close M current K4 channels ml, m3 ? Open Ca2' dependent m2, mA Os Open Ca dependent K4