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Filtering by: Creator Waite, Mariah E. Remove constraint Creator: Waite, Mariah E. Advisor Schuster, Martin Remove constraint Advisor: Schuster, Martin

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  • Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

    Creator:
    Asfahl, Kyle L.
    Abstract:
    Cell-cell communication in bacteria is understood to facilitate the coordination of population-wide cooperative behavior in the form of concerted gene expression. The opportunistic pathogen Pseudomonas aeruginosa uses such a communication mechanism to regulate a large group of genes important to virulence strategies in this bacterium. This general mechanism of communication...
    Resource Type:
    Dissertation

  • The Social Interactions of Pseudomonas aeruginosa

    Creator:
    Smith, Parker
    Abstract:
    Pseudomonas aeruginosa is a ubiquitous environmental microbe, opportunistic pathogen, and a highly social organism. P. aeruginosa utilizes a wide array of cooperative behaviors to adapt to the environmental conditions around it. These behaviors include quorum sensing (QS), a form a cell-to-cell signaling that coordinates the expression of secreted products in...
    Resource Type:
    Dissertation
    Full Text:
    ) Pyoverdine secretion by P. aeruginosa on an agar plate. (E) Light produced by bioluminescent Vibrio fischeri

  • Studies on the evolution and expression of the Type II ferripyoverdine receptor gene fpvAIIb in Pseudomonas aeruginosa

    Creator:
    Glover, Rochelle
    Abstract:
    When iron levels are low, the opportunistic pathogen Pseudomonas aeruginosa secretes the high-affinity iron-binding siderophore pyoverdine. The cognate ferripyoverdine receptor, FpvA, has gained attention as the most divergent gene in the organism’s genome, showing substantial evidence of positive selection. S-type pyocins, bacteriocins with specificity to Pseudomonads, enter cells through FpvA...
    Resource Type:
    Honors College Thesis
    Full Text:
    Key Words: Pseudomonas aeruginosa, pyoverdine, pyocin, evolution, expression Corresponding e-mail

  • Quorum sensing gene regulation in Pseudomonas aeruginosa

    Creator:
    Gupta, Rashmi
    Abstract:
    Pseudomonas aeruginosa is an opportunistic human pathogen that infects immunocompromised individuals such as those suffering from burns or the genetic disorder cystic fibrosis. This organism utilizes a cell-cell communication mechanism known as quorum sensing (QS) to coordinate virulence gene expression and biofilm formation. It has three interconnected QS systems, namely...
    Resource Type:
    Dissertation
    Full Text:
    Effect of ectopic pqsA-E expression on colony morphology ............................83 3.9 Colony

  • Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

    Creator:
    Mellbye, Brett L.
    Abstract:
    Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...
    Resource Type:
    Dissertation
    Full Text:
    system (Jensen et al., 2006). P. aeruginosa PhoR-PhoB is thought to function similarly to E. coli and