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Filtering by: Creator Moore, J. Keith Advisor Stormshak, Fredrick Committee Member Menino, Fred

Nongenomic action of progesterone inhibits oxytocin signaling through the ovine oxytocin receptor

Creator:

Bishop, Cecily V.

Abstract:

Experiments were conducted to characterize the nongenomic effects of progesterone (P4) on binding of oxytocin (OT) to the ovine oxytocin receptor (OTR) and signal transduction. The dose-response relationship of P4 to OT binding to the OTR in endometrium was examined. Progesterone interfered with the binding of OT to the OTR...

Resource Type:

Dissertation

Full Text:

appreciation to Dr Frank Moore and laboratory for their gift of the cell lines utilized in these experiments
Nongenomic inhibition of oxytocin binding by progesterone in ovine uteri

Creator:

Dunlap, Kathrin Anson

Abstract:

Effects of progesterone (P₄) and mifepristone (RU 486) on binding of oxytocin (OT) to its ovine uterine receptor (OTR) were studied in two experiments. Two additional experiments were conducted to evaluate specific binding sites for P4 in endometrial plasma membranes. In Exp. 1, ovariectomized ewes were injected with estradiol-17β (E₂)...

Resource Type:

Masters Thesis
Mechanisms of estradiol-17β-induced down-regulation of ovine uterine oxytocin receptors during the estrous cycle

Creator:

Hazzard, Timothy McLagan

Resource Type:

Dissertation