Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Kibler, Kelly M. Advisor Stormshak, Fredrick License All rights reserved

Nongenomic action of progesterone inhibits oxytocin signaling through the ovine oxytocin receptor

Creator:

Bishop, Cecily V.

Abstract:

Experiments were conducted to characterize the nongenomic effects of progesterone (P4) on binding of oxytocin (OT) to the ovine oxytocin receptor (OTR) and signal transduction. The dose-response relationship of P4 to OT binding to the OTR in endometrium was examined. Progesterone interfered with the binding of OT to the OTR...

Resource Type:

Dissertation

Full Text:

experiments over the last four years. I thank her laboratory technician Kristi M Crofoot for performing the
Involvement of myristoylated alanine-rich c kinase substrate (MARCKS) protein in prostaglandin F2α- induced secretion of oxytocin by the bovine corpus luteum

Creator:

Salli, Ugur

Abstract:

Prostaglandin F₂α (PGF₂α), a stimulatory hormone of luteal oxytocin secretion, is known to activate protein kinase C (PKC); however, the intracellular signals that promote exocytosis of oxytocin remain to be elucidated. Myristoylated alanine-rich C kinase substrate (MARCKS), a protein specifically phosphorylated by PKC, crosslinks actin filaments associated with the inner...

Resource Type:

Dissertation