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Filtering by: Creator Beaman, Jill A. Advisor Tanguay, Robert L. Committee Member Anderson, Kim

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Creator:

Goodale, Britton C.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...

Resource Type:

Dissertation

Full Text:

this large family of multi-ring structures and substituted derivatives is a substantial challenge