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Filtering by: Creator Rojas, Wilson Advisor Tanguay, Robert L. Resource Type Dissertation

Developmental toxicity of polycyclic aromatic hydrocarbons : defining mechanisms with systems-based transcriptional profiling

Creator:

Goodale, Britton C.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...

Resource Type:

Dissertation

Full Text:

preparation for the PAH body burden studies. Glenn Wilson conducted GC-MS analysis of PAH body burden
Chemical and biological approaches to identify vertebrate tissue regeneration pathways

Creator:

Sengupta, Sumitra

Abstract:

Numerous human conditions would be improved if therapies to encourage tissue regeneration were available. The goal of regenerative medicine is to encourage the body's intrinsic ability to repair and restore tissues lost by disease, injury or aging. While certain vertebrates have the inherent capacity to regenerate, mammals do not. To...

Resource Type:

Dissertation

Full Text:

regeneration in zebrafish. Development, 1995. 121(2): p. 347-57. 16. Poss, K.D., L.G. Wilson, and M.T