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Filtering by: Creator Chatterjee, Paroma Advisor Tanguay, Robert L.

Classifying polycyclic aromatic hydrocarbon bioactivities using phenotypic screening and transcriptomics in the developmental zebrafish model

Creator:

Geier, Mitra Celestine

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants that occur in complex mixtures. These environmental mixtures can consist of both parent PAHs and their derivatives. Several parent PAHs are known or suspected mutagens and/or carcinogens, and a handful of PAH derivatives are known to be more potent mutagens and/or carcinogens...

Resource Type:

Dissertation

Full Text:

guidance. Thanks must also go to Dr. Marc Elie, Dr. Leah Wehmas, Dr. Anna Chlebowski, Dr. Paroma
Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Creator:

Haggard, Derik

Abstract:

There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...

Resource Type:

Dissertation

Full Text:

, Mike Garland, Lindsay St. Mary, Paroma Chatterjee, Courtney Roper, and Gloria Garcia for our