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Filtering by: Subject Theophylline -- Physiological effect Advisor Traber, Maret G. Committee Member Jump, Donald B.

Embryogenesis is dependent upon 12-lipoxygenase, 5-lipoxygenase, and alpha-tocopherol to modulate polyunsaturated fatty acid status and the production of oxidized fatty acids in zebrafish, Embryogenesis is dependent upon 12-lipoxygenase, 5-lipoxygenase, and α-tocopherol to modulate polyunsaturated fatty acid status and the production of oxidized fatty acids in zebrafish

Creator:

Lebold, Katherine M.

Abstract:

Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are polyunsaturated fatty acids required for proper embryonic development, specifically neurodevelopment. However, little is known regarding their conversion to other metabolites during embryogenesis. The oxidation of ARA gives rise to the biologically active eicosanoids and the oxidation of DHA gives rise to the...

Resource Type:

Masters Thesis

Full Text:

, COX-2 regulates ovulation and embryonic implantation87, however no effect of COX-2 knockdown was