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Filtern nach: Advisor White, James D. Filter Advisor: White, James D. entfernen Committee Member Gable, Kevin Filter Committee Member: Gable, Kevin entfernen Degree Level Doctoral Filter Degree Level: Doctoral entfernen Degree Name Doctor of Philosophy (Ph.D.) Filter Degree Name: Doctor of Philosophy (Ph.D.) entfernen

Suchergebnisse

  • Studies toward the total synthesis of sanglifehrin A

    Schöpfer:
    Suttisintong, Khomson
    Abstract:
    Studies toward synthesis of subunits of sanglifehrin A, an immunosuppressant featuring a highly substituted [5,5]-spirolactam moiety as well as a 22-membered macrocycle are described. The macrolactone contains a peptidic backbone characterized by an unusual [beta]-substituted (S)-piperazic acid and (S)-m-hydroxyphenylalanine units. These studies resulted in the synthesis of advanced intermediate 358...
    Resource Type:
    Dissertation

  • Synthesis of furanoeremophilane sesquiterpenoids

    Schöpfer:
    Shanmugham, Meenakshi Sundaram
    Abstract:
    Two approaches to the tricyclic core of the furanoeremophilane sesquiterpenoids are described. The first approach entails a projected Diels-Alder/retro Diels-Alder reaction of an acetylenic oxazole 64. Construction of the pivotal aldehyde 67 commenced from ketone 68. The acetyenic moiety was then introduced via a Felkin-Ahn addition of lithiopropyne to aldehyde...
    Resource Type:
    Dissertation