Search Constraints

Start Over
Filtering by: Creator Johnson, Colin P. Remove constraint Creator: Johnson, Colin P. Advisor White, James D. Remove constraint Advisor: White, James D. File Format application/pdf Remove constraint File Format: application/pdf

Search Results

  • Studies towards the total synthesis of (-)-kendomycin

    Creator:
    Smits, Helmars
    Abstract:
    Studies towards the total synthesis of (−)-kendomycin (1), a bacterial metabolite with a unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediate 208, containing all of the carbon atoms of 1. A Dötz annulation between alkyne 122 and novel chromium carbenoid...
    Resource Type:
    Dissertation
    Full Text:
    ) p-TsNHNH2, EtOH, 4A MS, reflux 2) NaCNBH3, ZnCl2, EtOH reflux, 65% OMe OMe OMe MeO O HO