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Filtering by: Creator McAuliffe, Scott C. Advisor White, James D. Subject Nootropic agents -- Synthesis

Synthetic studies n bioactive natural products. Part I, An approach towards the nootrophic agent huperzine A. Part II, Synthesis of the tricarbonyl subunit of rapamycin

Creator:

Jeffrey, Scott C.

Resource Type:

Dissertation

Full Text:

rapamycin AN ABSTRACT OF THE DISSERTATION OF Scott C. Jeffrey for the degree of Doctor of Philosophy in
Natural product synthesis via cyclobutanes : part I, Asymmetric synthesis of (+)-byssochlamic acid, part II, An approach to the nootropic agent huperzine A

Creator:

Kim, Jungchul

Abstract:

PART I. Asymmetric syntheses of both natural (+)- and nonnatural (-)-byssochlamic acid via a [2+2] photoaddition-cycloreversion strategy are described. X-ray crystallographic analysis of the cyclohexylamine salt 99 showed that the structure of the monomethyl ester 100 from esterase hydrolysis of 44 was originally misassigned as 56. The enantiomeric relationship of...

Resource Type:

Dissertation

Full Text:

Deerberg, Duncan J. Wardrop, Carla Hassler, Sung-kee Kim, Christine S. Nylund, Scott J. Kemp, Roger